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Safinamide Mesylate (FCE28073)

Safinamide Mesylate (FCE28073)

Name: Safinamide Mesylate (FCE28073)
SKU: A10818

目录号: A10818

MAO 抑制剂

Safinamide Mesylate (FCE28073) Chemical Structure

CAS NO. 202825-46-5

Safinamide Mesylate是沙芬酰胺的甲磺酸盐，可选择性和可逆地抑制MAO-B，IC50为0.45μM。

库存：现货

规格	价格	数量
10 mg	￥ 511.00
50 mg	￥ 1,505.00
100 mg	￥ 5,117.00
10mM * 1mL in DMSO	￥ 917.00

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生物活性

Safinamide Mesylate是沙芬酰胺的甲磺酸盐，可选择性和可逆地抑制MAO-B，IC50为0.45μM。

靶点信息

MAO-B	MAO-A
98 nM	580 μM

溶解度 *

In vitro (25°C)	DMSO	78 mg/mL (195.75 mM)
	Water	78 mg/mL (195.75 mM)
	Ethanol	13 mg/mL (32.62 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.09 mL	125.47 mL	250.94 mL
0.5 mM	5.02 mL	25.09 mL	50.19 mL
1 mM	2.51 mL	12.55 mL	25.09 mL
5 mM	0.5 mL	2.51 mL	5.02 mL

*The above data is based on the productmolecular weight 398.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10818
作用机制	Inhibitor (抑制剂)
M. Wt	398.5
Formula	C17H19FN2O2.CH4O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	202825-46-5
Synonyms	FCE-28073(R-isomer), PNU-151774E, NW-1015
SMILES	C[C@@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O