Santacruzamate A
目录号: A14236
HDAC 抑制剂
Santacruzamate A(CAY10683)是一种强效且选择性的HDAC抑制剂,对HDAC2的IC50为119 pM,对其他HDACs的选择性超过3600倍。
Discription | Santacruzamate A (CAY10683) is a potent and selective HDAC inhibitor with IC50 of 119 pM for HDAC2, >3600-fold selectivity over other HDACs. | |||||
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Targets |
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Cell Research |
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目录号 | A14236 |
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分子式 | C15H22N2O3 |
分子量 | 278.35 |
CAS号 | 1477949-42-0 |
SMILES | CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1 |
其他名称 | CAY10683 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 47 mg/mL (168.85 mM) | |
Water | Insoluble | ||
Ethanol | 47 mg/mL (168.85 mM) | ||
In vivo | 5%DMSO+30%PEG300+5%TW80+H2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.93 mL | 179.63 mL | 359.26 mL |
0.5 mM | 7.19 mL | 35.93 mL | 71.85 mL |
1 mM | 3.59 mL | 17.96 mL | 35.93 mL |
5 mM | 0.72 mL | 3.59 mL | 7.19 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2