SAR-7334 HCl

Name: SAR-7334 HCl
SKU: A17237
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A17237

TRPC6 抑制剂

SAR7334 是一种新型、高效且生物利用度高的 TRPC6 通道抑制剂，为体内研究 TRPC 通道功能提供了新的机会。SAR7334 抑制 TRPC6、TRPC3 和 TRPC7 介导的细胞内 Ca(2+) 流入，其 IC50 分别为 9.5、282 和 226 nM，而 TRPC4 和 TRPC5 介导的 Ca(2+) 入口则未受影响。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
5mg	¥735.00	现货
10mg	¥1,050.00	现货
25mg	¥1,505.00	现货
50mg	¥1,995.00	现货
100mg	¥2,555.00	现货
200mg	¥3,640.00	现货
*10mM 1mL in DMSO**	¥770.00	现货
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Data Sheet

SDS

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生物活性

Discription	SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected.

产品信息

目录号	A17237
分子式	C21H24Cl3N3O
分子量	440.793
CAS号	1333207-63-8
SMILES	N#CC1=CC=C(O[C@H]2[C@H](N3C[C@H](N)CCC3)CC4=C2C=CC=C4)C(Cl)=C1.[H]Cl.[H]Cl
其他名称	SAR-7334; SAR 7334; SAR7334
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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