SAR125844

目录号: A21094

MET inhibitor

SAR125844

SAR125844 Chemical Structure

CAS NO. 1116743-46-4

SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays.

库存: 现货

规格 价格 数量
5 mg
¥ 756.00
10 mg
¥ 1,302.00
50 mg
¥ 3,864.00
100 mg
¥ 7,728.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays.
In vitro DMSO 11 mg/mL (19.97 mM)
Water <1 mg/mL
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.16 mL 90.81 mL 181.61 mL
0.5 mM 3.63 mL 18.16 mL 36.32 mL
1 mM 1.82 mL 9.08 mL 18.16 mL
5 mM 0.36 mL 1.82 mL 3.63 mL

*The above data is based on the productmolecular weight 550.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21094
作用机制 Inhibitor (抑制剂)
M. Wt 550.63
Formula C25H23FN8O2S2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1116743-46-4
Synonyms SAR 125844, SAR-125844
SMILES O=C(NCCN1CCOCC1)NC2=NC3=CC=C(SC4=NN=C5C=CC(C6=CC=C(F)C=C6)=NN54)C=C3S2

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