Saracatinib (AZD0530)

Name: Saracatinib (AZD0530)
SKU: A10108
Price: 280 CNY
Rating: 5 (4 reviews)

目录号: A10108

Src/Abl 抑制剂

4 篇发表文献

Saracatinib (AZD0530) 是一种高度选择性的、可口服的双特异性 Src/Abl 激酶抑制剂，其对 c-Src 和 Abl 激酶的 IC50 分别为 2.7 nM 和 30 nM。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥350.00	现货
25mg	¥595.00	现货
50mg	¥980.00	现货
100mg	¥1,505.00	现货
200mg	¥2,695.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Saracatinib (AZD0530)发表的4篇文献

Andromachi Lambrianidou, .et al. , Cell Signal, 2021, Apr;80:109912 PMID: 33388443

Chisato Naito, .et al. , Atherosclerosis, 2016, Mar;246:344-51 PMID: 26828753

Kenta Maruyama, .et al. , J Biol Chem, 2015, Apr 10; 290(15): 9377-9386 PMID: 25691576

Amanda L Jackson, .et al. , Expert Opin Emerg Drugs, 2015, Jun;20(2):331-46 PMID: 26001052

生物活性

Discription

Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10108
分子式	C27H32ClN5O5
分子量	542
CAS号	379231-04-6
SMILES	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 34 mg/mL (62.73 mM)
	Water	Insoluble
	Ethanol	30 mg/mL (55.35 mM)
In vivo	2% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.45 mL	92.25 mL	184.5 mL
0.5 mM	3.69 mL	18.45 mL	36.9 mL
1 mM	1.85 mL	9.23 mL	18.45 mL
5 mM	0.37 mL	1.85 mL	3.69 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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