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Saridegib is a potent and specific inhibitor of Smoothened (Smo), a key signaling transmembrane protein in the Hedgehog (Hh) pathway.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.81 mL | 99.06 mL | 198.11 mL |
| 0.5 mM | 3.96 mL | 19.81 mL | 39.62 mL |
| 1 mM | 1.98 mL | 9.91 mL | 19.81 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.96 mL |
*The above data is based on the productmolecular weight 504.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12966 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 504.77 |
| Formula | C29H48N2O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1037210-93-7 |
| Synonyms | IPI-926; Patidegib, IPI926, IPI 926 |
| SMILES | CC1=C(C[C@@]2([H])[C@@]3([H])CC[C@@]4([H])[C@]2(C)CC[C@@H](NS(C)(=O)=O)C4)[C@@]3([H])CC[C@@]([C@@H]5C)(C1)O[C@@]6([H])[C@@]5([H])NC[C@@H](C)C6 |
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