Saxagliptin (BMS-477118)

Name: Saxagliptin (BMS-477118)
SKU: A11109
Price: 140 CNY
Rating: 5 (5 reviews)

目录号: A11109

DPP-4 Inhibitor

5 篇发表文献

萨格列汀（BMS-477118）是一种新型的二肽基肽酶-4（DPP-4）抑制剂，其半抑制浓度（IC50）为50纳摩尔。

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Grouped product items
规格	价格	库存
5mg	¥315.00	现货
10mg	¥175.00	现货
25mg	¥420.00	现货
50mg	¥700.00	现货
100mg	¥1,085.00	现货
200mg	¥1,715.00	现货
*10mM 1mL in DMSO**	¥140.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Saxagliptin (BMS-477118)发表的5篇文献

Ki-Young Kim, .et al. , Pharmaceutics, 2024, Jan 13;16(1):106 PMID: 38258116

OHE El-Shoubashy, .et al. , JPC, 2020, 33, 59-70

Sato T, .et al. , Sci Rep, 2019, Dec 2;9(1):18094 PMID: 31792328

Chintan N. Koyani, .et al. , Front Physiol, 2018, 9: 1622 PMID: 30487758

Koyani CN, .et al. , Biochem Pharmacol, 2016, Dec 1;145:64-80 PMID: 28859968

生物活性

Discription

Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11109
分子式	C18H25N3O2
分子量	315.4
CAS号	361442-04-8
SMILES	C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N
其他名称	BMS-477118,Onglyza
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	62 mg/mL (196.57 mM)
	Water	62 mg/mL (196.57 mM)
	Ethanol	24 mg/mL (76.09 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.71 mL	158.53 mL	317.06 mL
0.5 mM	6.34 mL	31.71 mL	63.41 mL
1 mM	3.17 mL	15.85 mL	31.71 mL
5 mM	0.63 mL	3.17 mL	6.34 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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