微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
SB 203580是p38α和p38β的特异性抑制剂，可抑制MAPKAP激酶2和热激蛋白27的下游激活。
靶点信息
| p38 MAPK (THP-1 cells) | PKB (THP-1 cells) | |||
| 0.3 μM-0.5 μM | 3 μM-5 μM |
| In vitro (25°C) | DMSO | 40 mg/mL (105.97 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 4% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.5 mL | 132.49 mL | 264.97 mL |
| 0.5 mM | 5.3 mL | 26.5 mL | 52.99 mL |
| 1 mM | 2.65 mL | 13.25 mL | 26.5 mL |
| 5 mM | 0.53 mL | 2.65 mL | 5.3 mL |
*The above data is based on the productmolecular weight 377.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10824 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 377.4 |
| Formula | C21H16FN3OS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 152121-47-6 |
| Synonyms | SB-203580, SB203580 |
| SMILES | CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Asiatic acid
Asiatic acid常用于伤口愈合。亚洲酸具有抗氧化，抗炎和神经保护的特性。积雪草酸衍生物的合成可用作抗…
DBM 1285 dihydrochloride
DBM 1285 dihydrochloride是p38 MAPK抑制剂。在巨噬细胞和体内抑制p38磷酸化和LPS诱导的TNF-α产生。
TRC 051384
TRC 051384，属于取代的2-丙烯-1-酮类，是热休克蛋白70（HSP70）的有效诱导剂。HSP70的诱导是应激细胞的自然…
Keywords:购买 SB 203580 | SB 203580 供应商 | 订购 SB 203580 | SB 203580 价格 | SB 203580 生产商 | 订单 SB 203580 | SB 203580 代理商 | 购买 152121-47-6| 152121-47-6 供应商 | 订购 152121-47-6 | 152121-47-6 价格 | 152121-47-6 生产商 | 订单 152121-47-6 | 152121-47-6 代理商|buy SB 203580 | SB 203580 Supplier | purchase SB 203580 | SB 203580 cost | SB 203580 manufacturer | order SB 203580 | SB 203580 distributor | buy 152121-47-6| 152121-47-6 Supplier | purchase 152121-47-6 | 152121-47-6 cost | 152121-47-6 manufacturer | order 152121-47-6 | 152121-47-6 distributor