Adezmapimod (SB-203580)

Name: Adezmapimod (SB-203580)
SKU: A10824
Price: 175 CNY
Rating: 5 (12 reviews)

目录号: A10824

p38 MAPK 抑制剂

12 篇发表文献

SB 203580 是一种特异性抑制剂，针对 p38α 和 p38β，能够抑制下游的 MAPKAP kinase-2 和 heat shock protein 27 的激活。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥280.00	现货
25mg	¥315.00	现货
50mg	¥385.00	现货
100mg	¥665.00	现货
200mg	¥1,155.00	现货
500mg	¥1,995.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Adezmapimod (SB-203580)

SB 203580 hydrochloride

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Adezmapimod (SB-203580)发表的12篇文献

Jung Hyun Kang, .et al. , Food Sci Biotechnol, 2024, 33: 3629-3637

Masayuki Harada, .et al. , Cell Cycle, 2024, Feb;23(3):308-327 PMID: 38461418

Dan Mao, .et al. , J Oral Biosci, 2024, Mar;66(1):105-111 PMID: 38182046

Lei Zhang, .et al. , Stem Cell Reports, 2022, Jun 14;17(6):1428-1441 PMID: 35561683

Tomoyuki Hashimoto, .et al. , Ann Nucl Med, 2021, Aug 19 PMID: 34410619

Y Zou, .et al. , BMC Cancer, 2019, Oct 15;19(1):949 PMID: 31615459

Wei P, .et al. , Cell Death Dis, 2019, Sep 11;10(9):670 PMID: 31511493

Uwada J, .et al. , Cell Signal, 2019, Nov;63:109358 PMID: 31295519

Byungki Jang, .et al. , Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055

Uwada J, .et al. , Cell Signal, 2017, Jul;35:188-196 PMID: 28412413

ZHIQIANG ZHANG, .et al. , Mol Med Rep. , 2015, Jul;12(1):1499-505. PMID: 25815691

Choe YJ, .et al. , Int J Oncol., 2014, 44(3):761-8. PMID: 24366007

生物活性

Discription

SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10824
分子式	C21H16FN3OS
分子量	377.4
CAS号	152121-47-6
SMILES	CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
其他名称	SB-203580, SB203580
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	40 mg/mL (105.97 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.5 mL	132.49 mL	264.97 mL
0.5 mM	5.3 mL	26.5 mL	52.99 mL
1 mM	2.65 mL	13.25 mL	26.5 mL
5 mM	0.53 mL	2.65 mL	5.3 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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