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SB 216763

目录号: A10825
GSK-3 抑制剂
SB 216763 是一种有效且选择性的细胞渗透性 ATP 竞争性抑制剂,针对 GSK3α 具有 34 nM 的 IC50 值(对 GSK3β 的效力相似)。
Grouped product items
规格 价格 库存 数量
2mg
¥175.00
现货
5mg
¥245.00
现货
10mg
¥385.00
现货
25mg
¥875.00
现货
50mg
¥1,365.00
现货
100mg
¥2,345.00
现货
500mg
¥5,880.00
现货
10mM * 1mL in DMSO
¥280.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A10825
分子式 C19H12Cl2N2O2
分子量 371.2
CAS号 280744-09-4
SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl
其他名称 SB-216763, SB216763
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO 21 mg/mL (56.56 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.94 mL 134.7 mL 269.4 mL
0.5 mM 5.39 mL 26.94 mL 53.88 mL
1 mM 2.69 mL 13.47 mL 26.94 mL
5 mM 0.54 mL 2.69 mL 5.39 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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