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SB 218078是检查点激酶1（Chk1）的抑制剂，对其他蛋白激酶具有选择性（Chk1，cdc2和PKC的IC50值分别为15、250和1000 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.42 mL | 127.1 mL | 254.2 mL |
| 0.5 mM | 5.08 mL | 25.42 mL | 50.84 mL |
| 1 mM | 2.54 mL | 12.71 mL | 25.42 mL |
| 5 mM | 0.51 mL | 2.54 mL | 5.08 mL |
*The above data is based on the productmolecular weight 393.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15480 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 393.39 |
| Formula | C24H15N3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 135897-06-2 |
| Synonyms | SB218078, SB-218078 |
| SMILES | C1CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C1O2)C7=C53)C(=O)NC6=O |
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