SB 334867

Name: SB 334867
SKU: A12786
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A12786

OX1 receptor 拮抗剂

1 篇发表文献

SB 334867 是一种选择性的非肽类orexin OX1 受体拮抗剂。其 pKb 值分别为 7.2 和小于 5，用于抑制表达人类 OX1 和 OX2 受体的 CHO 细胞中的细胞内 Ca2+ 释放。在体内通过系统给药后，可阻断 orexin-A 引起的梳理和进食行为。

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规格	价格	库存
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥1,015.00	现货
50mg	¥1,715.00	现货
100mg	¥3,360.00	现货
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Data Sheet

SDS

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Adooq用户使用SB 334867发表的1篇文献

Tony Ngo, .et al. , Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882

生物活性

Discription

SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12786
分子式	C17H13N5O2
分子量	319.32
CAS号	249889-64-3
SMILES	CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4
其他名称	SB334867,SB-334867
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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