SB 415286

Name: SB 415286
SKU: A11061
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A11061

GSK-3 抑制剂

SB 415286 是一种强效且选择性的细胞渗透性、ATP竞争性抑制剂，针对 GSK3α 具有 78 nM 的 IC50 值（对 GSK3β 的效力相似）和 31 nM 的 Ki 值。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥805.00	现货
50mg	¥1,365.00	现货
100mg	¥2,205.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.

Targets

Target	Value

产品信息

目录号	A11061
分子式	C16H10ClN3O5
分子量	359.7
CAS号	264218-23-7
SMILES	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)[N+](=O)[O-]
其他名称	SB-415286, SB415286
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	63 mg/mL (175.13 mM)
	Water	Insoluble
	Ethanol	63 mg/mL (175.13 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.8 mL	139 mL	278.01 mL
0.5 mM	5.56 mL	27.8 mL	55.6 mL
1 mM	2.78 mL	13.9 mL	27.8 mL
5 mM	0.56 mL	2.78 mL	5.56 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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