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SB-423557

SB-423557

Name: SB-423557
SKU: A21169

目录号: A21169

alcium-sensing receptor (CaR) antagonist

SB-423557 Chemical Structure

CAS NO. 351490-26-1

SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM).

库存：现货

规格	价格	数量
1 mg	￥ 2,240.00
5 mg	￥ 6,720.00
10 mg	￥ 11,200.00

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生物活性

SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM).

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.52 mL	107.62 mL	215.24 mL
0.5 mM	4.3 mL	21.52 mL	43.05 mL
1 mM	2.15 mL	10.76 mL	21.52 mL
5 mM	0.43 mL	2.15 mL	4.3 mL

*The above data is based on the productmolecular weight 464.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21169
作用机制	Antagonist (拮抗剂)
M. Wt	464.6
Formula	C28H36N2O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	351490-26-1
Synonyms	SB423557, SB 423557
SMILES	O=C(OCC)CCC1=CC=C(C#N)C(OC[C@H](O)CNC(C)(C)CC2CC3=C(C=CC=C3)C2)=C1