SB-505124

Name: SB-505124
SKU: A11157
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A11157

ALK5 抑制剂

SB-505124 是一种选择性的转化生长因子-β型 I 受体（ALK5）、ALK4 和 ALK7 的抑制剂（IC50 值分别为 ALK5 为 47 nM 和 ALK4 为 129 nM）。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥385.00	现货
10mg	¥700.00	现货
25mg	¥1,505.00	现货
50mg	¥2,695.00	现货
100mg	¥3,990.00	现货
500mg	¥8,505.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

SB-505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5), ALK4 and ALK7 (IC50 values are 47 and 129 nM for ALK5 and ALK4 respectively).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11157
分子式	C20H21N3O2
分子量	335.4
CAS号	694433-59-5
SMILES	CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4
其他名称	SB505124
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	65 mg/mL (193.8 mM)
	Water	Insoluble
	Ethanol	65 mg/mL (193.8 mM)
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	7.1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.82 mL	149.08 mL	298.15 mL
0.5 mM	5.96 mL	29.82 mL	59.63 mL
1 mM	2.98 mL	14.91 mL	29.82 mL
5 mM	0.6 mL	2.98 mL	5.96 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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