SB-742457

Name: SB-742457
SKU: A14092

目录号: A14092

5-HT6 receptor 拮抗剂

SB-742457 Chemical Structure

CAS NO. 607742-69-8

SB-742457是一种选择性的5-HT6受体拮抗剂，具有认知，记忆和增强学习的作用。

库存：现货

规格	价格	数量
5 mg	￥ 630.00
10 mg	￥ 1,050.00
25 mg	￥ 2,100.00
10mM * 1mL in DMSO	￥ 840.00

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生物活性

SB-742457是一种选择性的5-HT6受体拮抗剂，具有认知，记忆和增强学习的作用。

靶点信息

5-HT6
9.63(pKi)

溶解度 *

In vitro (25°C)	DMSO	72 mg/mL (203.7 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (5.65 mM)
In vivo	2% DMSO, 48% PEG300, 2% Tween 80 and 48% water	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.29 mL	141.47 mL	282.93 mL
0.5 mM	5.66 mL	28.29 mL	56.59 mL
1 mM	2.83 mL	14.15 mL	28.29 mL
5 mM	0.57 mL	2.83 mL	5.66 mL

*The above data is based on the productmolecular weight 353.444. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14092
作用机制	Antagonist (拮抗剂)
M. Wt	353.444
Formula	C19H19N3O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	607742-69-8
Synonyms	GSK 742457, SB742457, SB 742457, GSK742457, SB-742,457
SMILES	C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4