SB225002
目录号: A14209
CXCR2 拮抗剂
SB225002 是一种高效且选择性的 CXCR2 拮抗剂，其 IC50 为 22 nM，用于抑制白细胞介素 IL-8 与 CXCR2 的结合，对其他测试的 7-TMRs 选择性超过 150 倍。
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生物活性
| Discription | SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested. | |||||
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| Cell Research |
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产品信息
| 目录号 | A14209 |
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| 分子式 | C13H10BrN3O4 |
| 分子量 | 352.14 |
| CAS号 | 182498-32-4 |
| SMILES | C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br |
| 其他名称 | SB-225002, SB 225002 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 64 mg/mL (181.74 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 3 mg/mL (8.51 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.4 mL | 141.99 mL | 283.98 mL |
| 0.5 mM | 5.68 mL | 28.4 mL | 56.8 mL |
| 1 mM | 2.84 mL | 14.2 mL | 28.4 mL |
| 5 mM | 0.57 mL | 2.84 mL | 5.68 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 SB225002 | SB225002 供应商 | SB225002 花费 | SB225002 生产商 | 订购 SB225002 | SB225002 代理商
| 购买 182498-32-4 | 182498-32-4 供应商 | 182498-32-4 花费 | 182498-32-4 生产商 | 订购 182498-32-4 | 182498-32-4 代理商