SB265610

Name: SB265610
SKU: A14195
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A14195

CXCR2 拮抗剂

SB 265610 是一种非肽类、异位的 CXCR2 逆向激动剂（Kd = 2.51 nM），通过与激动剂结合部位不同的区域结合来阻止受体激活。它不与相关的 CXCR1 受体结合。已经证明，它能够在体外和在大鼠高氧诱导的肺损伤模型中阻止中性粒细胞趋化。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
5mg	¥595.00	现货
10mg	¥1,015.00	现货
25mg	¥2,065.00	现货
50mg	¥4,060.00	现货
100mg	¥5,845.00	现货
500mg	¥12,075.00	现货
*10mM 1mL in DMSO**	¥875.00	现货
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Data Sheet

SDS

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生物活性

Discription

SB 265610 is a nonpeptide, allosteric, inverse agonist of CXCR2 (Kd = 2.51 nM) that prevents receptor activation by binding to a region distinct from the agonist binding site. It does not bind to the related CXCR1 receptor.1 It has been shown to prevent neutrophil chemotaxis both in vitro and in a rat model of hyperoxia-induced lung injury.

Targets

Target	Value

产品信息

目录号	A14195
分子式	C14H9BrN6O
分子量	357.16
CAS号	211096-49-0
SMILES	C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C3=NNN=C23)C#N)Br
其他名称	SB 265610,SB-265610
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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