SBI-0206965

Name: SBI-0206965
SKU: A15795
Price: 210 CNY
Rating: 5 (2 reviews)

目录号: A15795

ULK1 抑制剂

2 篇发表文献

SBI-0206965 是一种强效、选择性且细胞渗透性的自噬激酶 ULK1 抑制剂，其对 ULK1 激酶活性的 IC50 为 108 nM，对高度相关的激酶 ULK2 的 IC50 为 711 nM。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥665.00	现货
25mg	¥1,190.00	现货
50mg	¥1,960.00	现货
100mg	¥3,080.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用SBI-0206965发表的2篇文献

SR Bonam, .et al. , Cells, 2020, May; 9(5): 1321 PMID: 32466347

Altea Rocchi, .et al. , PLoS Genet, 2017, Aug; 13(8): e1006962 PMID: 28806762

生物活性

Discription

SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 .

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15795
分子式	C21H21BrN4O5
分子量	489.32
CAS号	1884220-36-3
SMILES	CNC(=O)C1=CC=CC=C1OC2=NC(=NC=C2Br)NC3=CC(=C(C(=C3)OC)OC)OC
其他名称	SBI 0206965, SBI0206965
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	90 mg/mL (183.92 mM)
	Water	Insoluble
	Ethanol	Warmed: 9 mg/mL (18.39 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.44 mL	102.18 mL	204.37 mL
0.5 mM	4.09 mL	20.44 mL	40.87 mL
1 mM	2.04 mL	10.22 mL	20.44 mL
5 mM	0.41 mL	2.04 mL	4.09 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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