SC-43

Name: SC-43
SKU: A22295
Price: 630 CNY
Rating: 5 (288 reviews)

目录号: A22295

SHP-1 (PTPN6) 激动剂

SC-43，一种索拉非尼衍生物，是一种强效且可口服的 SHP-1 (PTPN6) 激动剂。SC-43 抑制 STAT3 的磷酸化并诱导细胞凋亡。SC-43 具有抗纤维化和抗癌效果。

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Grouped product items
规格	价格	库存
1mg	¥630.00	现货
5mg	¥1,330.00	现货
10mg	¥1,960.00	现货
25mg	¥3,710.00	现货
50mg	¥5,320.00	现货
100mg	¥6,860.00	现货
*10mM 1mL in DMSO**	¥1,540.00	现货
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Data Sheet

SDS

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生物活性

Discription	SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects.

产品信息

目录号	A22295
分子式	C21H13ClF3N3O2
分子量	431.8
CAS号	1400989-25-4
SMILES	O=C(NC1=CC=CC(OC2=CC=C(C#N)C=C2)=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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