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SC 560是一种COX-1选择性抑制剂,IC50 值为9 nM。可以用作研究COX-1衍生的PG在炎症和疼痛中的作用的药理学工具。
In vitro | DMSO | 61 mg/mL (172.93 mM) | |
Water | Insoluble | ||
Ethanol | 61 mg/mL (172.93 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.35 mL | 141.75 mL | 283.49 mL |
0.5 mM | 5.67 mL | 28.35 mL | 56.7 mL |
1 mM | 2.83 mL | 14.17 mL | 28.35 mL |
5 mM | 0.57 mL | 2.83 mL | 5.67 mL |
*The above data is based on the productmolecular weight 352.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13023 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 352.74 |
Formula | C17H12ClF3N2O |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 188817-13-2 |
Synonyms | SC-560, SC560 |
SMILES | ClC1=CC=C(C=C1)C2=CC(C(F)(F)F)=NN2C(C=C3)=CC=C3OC |
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