SD-06

Name: SD-06
SKU: A11563
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A11563

p38 MAPK 抑制剂

SD-06 是一种 p38 MAP 激酶抑制剂；它抑制 p38α 的 IC50 值为 170 nM，并且能抑制大鼠 LPS 刺激下的 TNF-释放（在 1mg/kg, po 的剂量下抑制率为 83%）。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥525.00	现货
25mg	¥980.00	现货
50mg	¥1,610.00	现货
100mg	¥2,450.00	现货
200mg	¥3,430.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription	SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).

产品信息

目录号	A11563
分子式	C20H20ClN5O2
分子量	397.87
CAS号	271576-80-8
SMILES	C1CN(CCC1C2=C(C(=NN2)C3=CC=C(C=C3)Cl)C4=NC=NC=C4)C(=O)CO
其他名称	SD 06, SD06
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (193.53 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (5.02 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.13 mL	125.67 mL	251.34 mL
0.5 mM	5.03 mL	25.13 mL	50.27 mL
1 mM	2.51 mL	12.57 mL	25.13 mL
5 mM	0.5 mL	2.51 mL	5.03 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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