Selinexor trans-isomer

目录号: A22648
CRM1-selective 抑制剂
Selinexor trans-isomer 是 Selinexor 或 KPT-330 的反式异构体,它是一种选择性抑制核输出的 CRM1 抑制剂。它抑制蛋白质从核内运输,并在间皮瘤细胞中诱导细胞周期阻滞和凋亡。
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1mg
¥210.00
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2mg
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5mg
¥455.00
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10mg
¥595.00
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25mg
¥1,330.00
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50mg
¥2,450.00
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100mg
¥3,640.00
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生物活性
Discription Selinexor trans-isomer is a trans-isomer of Selinexor or KPT-330, which is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells.
产品信息
目录号 A22648
分子式 C17H11F6N7O
分子量 443.31
CAS号 1421923-86-5
SMILES O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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