Senicapoc (ICA-17043)

目录号: A11568
Gardos channel blocker
Senicapoc(ICA-17043)是一种效力强大且选择性高的Gardos 通道阻断剂,其 IC50 值为 11 nM。它能阻断人类红细胞(RBCs)中由 Ca2+ 引起的铷通量,IC50 值为 11 nM,并且以 IC50 值 30 nM 抑制红细胞脱水。
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规格 价格 库存 数量
5mg
¥175.00
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10mg
¥315.00
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25mg
¥490.00
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50mg
¥665.00
现货
100mg
¥945.00
现货
200mg
¥1,435.00
现货
10mM * 1mL in DMSO
¥210.00
现货
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生物活性
Discription Senicapoc (ICA-17043) is a potent and selective Gardos channel blocker with IC50 value of 11 nM. It blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.
产品信息
目录号 A11568
分子式 C20H15F2NO
分子量 323.34
CAS号 289656-45-7
SMILES O=C(C(C1=CC=CC=C1)(C2=CC=C(C=C2)F)C3=CC=C(F)C=C3)N
其他名称 ICA 17043, ICA17043
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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