SF2523
SF2523 是一种高度选择性和有效的 PI3K 抑制剂，其 IC50 分别为 PI3Kα 34 nM、PI3Kγ 158 nM、DNA-PK 9 nM、BRD4 241 nM 和 mTOR 280 nM。
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生物活性
| Discription | SF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively. | |||||
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产品信息
| 目录号 | A20557 |
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| 分子式 | C19H17NO5S |
| 分子量 | 371.41 |
| CAS号 | 1174428-47-7 |
| SMILES | O=C1C=C(N2CCOCC2)OC3=C1SC=C3C4=CC=C(OCCO5)C5=C4 |
| 其他名称 | SF 2523, SF-2523 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 29 mg/mL (78.08 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (18.84 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.92 mL | 134.62 mL | 269.24 mL |
| 0.5 mM | 5.38 mL | 26.92 mL | 53.85 mL |
| 1 mM | 2.69 mL | 13.46 mL | 26.92 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1174428-47-7 | 1174428-47-7 供应商 | 1174428-47-7 花费 | 1174428-47-7 生产商 | 订购 1174428-47-7 | 1174428-47-7 代理商