SGC 707
目录号: A15450
PRMT3 抑制剂
SGC 707 是一种强效的 PRMT3 的选择性变构抑制剂(IC50 = 50 nM),对其他甲基转移酶和非表观遗传靶标具有超过100倍的选择性。
Discription | SGC 707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. | |||||
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Cell Research |
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目录号 | A15450 |
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分子式 | C16H18N4O2 |
分子量 | 298.3 |
CAS号 | 1687736-54-4 |
SMILES | C1CCN(C1)C(=O)CNC(=O)NC2=CC3=C(C=C2)C=NC=C3 |
其他名称 | SGC707, SGC-707 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 51 mg/mL (170.95 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 51 mg/mL (170.95 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 33.52 mL | 167.62 mL | 335.23 mL |
0.5 mM | 6.7 mL | 33.52 mL | 67.05 mL |
1 mM | 3.35 mL | 16.76 mL | 33.52 mL |
5 mM | 0.67 mL | 3.35 mL | 6.7 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2