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SGC-CBP30是一种有效且选择性的CREBBP（CBP）和EP300抑制剂，无细胞试验中IC50分别为21 nM和38 nM。它们是一般的转录共激活因子。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.64 mL | 98.22 mL | 196.45 mL |
| 0.5 mM | 3.93 mL | 19.64 mL | 39.29 mL |
| 1 mM | 1.96 mL | 9.82 mL | 19.64 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.93 mL |
*The above data is based on the productmolecular weight 509.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13227 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 509.04 |
| Formula | C28H33ClN4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1613695-14-9 |
| Synonyms | SGCCBP30,SGC CBP30 |
| SMILES | CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)CCC4=CC(=C(C=C4)OC)Cl)C[C@H](C)N5CCOCC5 |
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