SGI-7079
目录号: A15864
Axl 抑制剂
SGI-7079，一种新型选择性Axl抑制剂，以剂量依赖方式抑制肿瘤生长，并可能成为克服EGFR抑制剂耐药性的潜在治疗靶标。
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生物活性
| Discription | SGI-7079 ,a novel selective Axl inhibitor, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance. | ||
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| Targets |
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产品信息
| 目录号 | A15864 |
|---|---|
| 分子式 | C26H26FN7 |
| 分子量 | 455.53 |
| CAS号 | 1239875-86-5 |
| SMILES | N#CCC1=CC=CC(C2=C3C(NC=C3C)=NC(NC4=CC=C(N5CCN(C)CC5)C(F)=C4)=N2)=C1 |
| 其他名称 | SGI7079, SGI 7079 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 77 mg/mL (169.03 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.95 mL | 109.76 mL | 219.52 mL |
| 0.5 mM | 4.39 mL | 21.95 mL | 43.9 mL |
| 1 mM | 2.2 mL | 10.98 mL | 21.95 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.39 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1239875-86-5 | 1239875-86-5 供应商 | 1239875-86-5 花费 | 1239875-86-5 生产商 | 订购 1239875-86-5 | 1239875-86-5 代理商