SGX-523

Name: SGX-523
SKU: A10839
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A10839

c-Met 抑制剂

SGX-523 是一种口服生物利用度高的小分子，能特异性结合到 c-Met 蛋白（或称 HGFR），阻止 HGF 的结合并中断 MET 信号通路。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
2mg	¥210.00	现货
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥770.00	现货
50mg	¥1,225.00	现货
100mg	¥2,065.00	现货
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Data Sheet

SDS

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生物活性

Discription

SGX-523 is an orally bioavailable small molecule, specifically binds to c-Met protein, or HGFR, preventing binding of HGF and disrupting the MET signaling pathway.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10839
分子式	C18H13N7S
分子量	359.4
CAS号	1022150-57-7
SMILES	CN1C=C(C=N1)C2=NN3C(=NN=C3SC4=CC5=C(C=C4)N=CC=C5)C=C2
其他名称	SGX523
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 3 mg/mL (8.34 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose+0.2% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.82 mL	139.12 mL	278.24 mL
0.5 mM	5.56 mL	27.82 mL	55.65 mL
1 mM	2.78 mL	13.91 mL	27.82 mL
5 mM	0.56 mL	2.78 mL	5.56 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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