SHIP2-IN-1
目录号: A19650
SHIP2 抑制剂
SHIP2-IN-1 是一种强效的 SHIP2 抑制剂,能够抑制 SHIP2 活性,其 IC50 为 2 微摩尔。SHIP2-IN-1 通过在 Ser9 残基上的磷酸化作用阻断 GSK3β 的激活。SHIP2-IN-1 用于阿尔茨海默病的研究。
Discription | SHIP2-IN-1 is a potent SHIP2 inhibitor, inhibits SHIP2 activity, with an IC50 of 2 ?M. SHIP2-IN-1 blocks GSK3β activation by phosphorylation at the Ser9 residue. SHIP2-IN-1 is used in the research of Alzheimer??s disease. |
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目录号 | A19650 |
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分子式 | C17H13Cl2FN4O |
分子量 | 379.22 |
CAS号 | 2252247-80-4 |
SMILES | FC1=C(Cl)C([C@@H](C)OC2=CN=CC(C3=CN=C(N)N=C3)=C2)=C(Cl)C=C1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2