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Silodosin (Rapaflo)是具有高尿嘧啶选择性的α1-肾上腺素受体拮抗剂。它几乎不引起体位性低血压（与其他α1阻滞剂相反）。
靶点信息
| α1-adrenergic receptor | ||||
| In vitro | DMSO | 97 mg/mL (195.74 mM) | |
| Water | Insoluble | ||
| Ethanol | 97 mg/mL (195.74 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.18 mL | 100.91 mL | 201.82 mL |
| 0.5 mM | 4.04 mL | 20.18 mL | 40.36 mL |
| 1 mM | 2.02 mL | 10.09 mL | 20.18 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
*The above data is based on the productmolecular weight 495.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10843 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 495.5 |
| Formula | C25H32F3N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 160970-54-7 |
| Synonyms | KAD 3213, KMD 3213 |
| SMILES | CC(CC1=CC2=C(C(=C1)C(=O)N)N(CC2)CCCO)NCCOC3=CC=CC=C3OCC(F)(F)F |
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