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SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.55 mL | 117.77 mL | 235.55 mL |
| 0.5 mM | 4.71 mL | 23.55 mL | 47.11 mL |
| 1 mM | 2.36 mL | 11.78 mL | 23.55 mL |
| 5 mM | 0.47 mL | 2.36 mL | 4.71 mL |
*The above data is based on the productmolecular weight 424.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20091 |
|---|---|
| M. Wt | 424.54 |
| Formula | C21H20N4O2S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1862237-99-7 |
| Synonyms | PROTAC Sirt2-binding moiety 1 |
| SMILES | O=C(NC1=NC=C(CC2=CC=CC(OCC#C)=C2)S1)CSC3=NC(C)=CC(C)=N3 |
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