Sitagliptin phosphate monohydrate

Name: Sitagliptin phosphate monohydrate
SKU: A10848
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A10848

DDP-4 抑制剂

西格列汀磷酸盐是一种抗糖尿病（降血糖）药物，属于二肽基肽酶-4（DPP-4）类。抑制DPP-4酶被认为可以增加胰高血糖素样肽-1（GLP-1），它抑制胰高血糖素的释放，刺激胰岛素的释放，并降低血糖水平。

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Grouped product items
规格	价格	库存
100mg	¥315.00	现货
200mg	¥385.00	现货
500mg	¥665.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Sitagliptin phosphate is an anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.

Targets

Target	Value

产品信息

目录号	A10848
分子式	C16H15F6N5O.H3PO4.H2O
分子量	523.3
CAS号	654671-77-9
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O
其他名称	Januvia, MK-0431
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	85 mg/mL (162.42 mM)
	Water	35 mg/mL (66.88 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.11 mL	95.55 mL	191.09 mL
0.5 mM	3.82 mL	19.11 mL	38.22 mL
1 mM	1.91 mL	9.55 mL	19.11 mL
5 mM	0.38 mL	1.91 mL	3.82 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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