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Sitaxsentan (IPI 1040; TBC-11251) is a selective endothelin A (ETA) receptor antagonist. Antihypertensive. Sitaxsentan is used in treatment of chronic heart failure.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.98 mL | 109.91 mL | 219.83 mL |
| 0.5 mM | 4.4 mL | 21.98 mL | 43.97 mL |
| 1 mM | 2.2 mL | 10.99 mL | 21.98 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
*The above data is based on the productmolecular weight 454.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11565 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 454.9 |
| Formula | C18H15ClN2O6S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 184036-34-8 |
| Synonyms | IPI 1040, IPI1040, IPI-1040; TBC-11251, TBC11251, TBC 11251 |
| SMILES | O=S(C1=C(C(CC2=CC3=C(C=C2C)OCO3)=O)SC=C1)(NC4=C(C(C)=NO4)Cl)=O |
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