Sitravatinib (MGCD516)
目录号: A16259
RTK 抑制剂
Sitravatinib 是一种新型小分子抑制剂,针对多种参与驱动肉瘤细胞生长的 RTKs(受体酪氨酸激酶)。
Discription | Sitravatinib is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. | ||
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Targets |
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目录号 | A16259 |
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分子式 | C33H29F2N5O4S |
分子量 | 629.68 |
CAS号 | 1123837-84-2 |
SMILES | O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=C5C(C=C(C6=NC=C(CNCCOC)C=C6)S5)=NC=C4)C(F)=C3 |
其他名称 | MGCD516, MG516 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 98 mg/mL (155.63 mM) | |
Water | Insoluble | ||
Ethanol | 98 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 15.88 mL | 79.41 mL | 158.81 mL |
0.5 mM | 3.18 mL | 15.88 mL | 31.76 mL |
1 mM | 1.59 mL | 7.94 mL | 15.88 mL |
5 mM | 0.32 mL | 1.59 mL | 3.18 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2