Sitravatinib (MGCD516)

Name: Sitravatinib (MGCD516)
SKU: A16259

目录号: A16259

RTK 抑制剂

Sitravatinib (MGCD516) Chemical Structure

CAS NO. 1123837-84-2

Sitravatinib是一种新型小分子抑制剂，靶向多种参与驱动肉瘤细胞生长的RTK。

库存：现货

规格	价格	数量
5 mg	￥ 490.00
10 mg	￥ 770.00
50 mg	￥ 1,960.00

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生物活性

Sitravatinib是一种新型小分子抑制剂，靶向多种参与驱动肉瘤细胞生长的RTK。

溶解度 *

In vitro	DMSO	98 mg/mL (155.63 mM)
	Water	Insoluble
	Ethanol	98 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.88 mL	79.41 mL	158.81 mL
0.5 mM	3.18 mL	15.88 mL	31.76 mL
1 mM	1.59 mL	7.94 mL	15.88 mL
5 mM	0.32 mL	1.59 mL	3.18 mL

*The above data is based on the productmolecular weight 629.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16259
作用机制	Inhibitor (抑制剂)
M. Wt	629.68
Formula	C33H29F2N5O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1123837-84-2
Synonyms	MGCD516, MG516
SMILES	O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=C5C(C=C(C6=NC=C(CNCCOC)C=C6)S5)=NC=C4)C(F)=C3