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Sivelestat sodium salt

目录号: A14073
Neutrophil elastase 抑制剂
Sivelestat 钠盐是一种选择性的白细胞弹性蛋白酶抑制剂(IC50 = 44 nM),在其他多种蛋白酶上没有活性。它能抑制 NF-kB 激活和体外 LTB4 诱导的中性粒细胞迁移。
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规格 价格 库存 数量
2mg
¥175.00
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5mg
¥350.00
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10mg
¥455.00
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25mg
¥945.00
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50mg
¥1,645.00
现货
10mM * 1mL in DMSO
¥490.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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Adooq用户使用Sivelestat sodium salt 发表的1篇文献
  • Shasha He, .et al. , Nature Biomedical Engineering, 2023, 7: 281-297
  • 生物活性
    Discription Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
    产品信息
    目录号 A14073
    分子式 C20H21N2NaO7S
    分子量 456.44
    CAS号 150374-95-1
    SMILES CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
    其他名称 ONO-5046
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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