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Sivelestat sodium hydrate (ONO-5046 sodium hydrate)

Sivelestat sodium hydrate (ONO-5046 sodium hydrate)

Name: Sivelestat sodium hydrate (ONO-5046 sodium hydrate)
SKU: A16137

目录号: A16137

Neutrophil elastase 抑制剂

Sivelestat sodium hydrate (ONO-5046 sodium hydrate) Chemical Structure

CAS NO. 201677-61-4

Sivelestat sodium hydrate (ONO-5046 sodium hydrate)是人嗜中性粒细胞弹性蛋白酶的竞争性抑制剂，还抑制从兔，大鼠，仓鼠和小鼠获得的白细胞弹性蛋白酶。

库存：现货

规格	价格	数量
10 mg	￥ 560.00
50 mg	￥ 1,820.00

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生物活性

Sivelestat sodium hydrate (ONO-5046 sodium hydrate)是人嗜中性粒细胞弹性蛋白酶的竞争性抑制剂，还抑制从兔，大鼠，仓鼠和小鼠获得的白细胞弹性蛋白酶。

靶点信息

neutrophil elastase

溶解度 *

In vitro	DMSO	91 mg/mL (172.18 mM)
	Water	Insoluble
	Ethanol	91 mg/mL (172.18 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.92 mL	94.61 mL	189.21 mL
0.5 mM	3.78 mL	18.92 mL	37.84 mL
1 mM	1.89 mL	9.46 mL	18.92 mL
5 mM	0.38 mL	1.89 mL	3.78 mL

*The above data is based on the productmolecular weight 528.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16137
作用机制	Inhibitor (抑制剂)
M. Wt	528.51
Formula	C20H21N2O7S.4H2O.Na
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	201677-61-4
Synonyms	ONO5046-Na, EI546 sodium, LY544349 sodium
SMILES	O=S(C1=CC=C(OC(C(C)(C)C)=O)C=C1)(NC2=C(C(NCC([O-])=O)=O)C=CC=C2)=O.[Na+].O.O.O.O