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SJ 172550是第一种MD50抑制剂，EC50为0.84 uM；与MDMX可逆结合，并有效杀死其中放大了MDMX表达的成视网膜细胞瘤细胞。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.32 mL | 116.59 mL | 233.17 mL |
| 0.5 mM | 4.66 mL | 23.32 mL | 46.63 mL |
| 1 mM | 2.33 mL | 11.66 mL | 23.32 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
*The above data is based on the productmolecular weight 428.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15352 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 428.87 |
| Formula | C22H21ClN2O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 431979-47-4 |
| Synonyms | SJ172550, SJ-172550 |
| SMILES | CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC |
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