SKI-178

Name: SKI-178
SKU: A22510
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A22510

SphK1 inhibitor

SKI-178 是一种鞘氨醇激酶1（SphK1）抑制剂（IC50 = 0.1-1.8 μM）。在人类急性髓系白血病细胞系中诱导 CDK1-依赖的凋亡。在体内有效。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥385.00	现货
10mg	¥665.00	现货
25mg	¥1,540.00	现货
50mg	¥2,485.00	现货
100mg	¥3,780.00	现货
500mg	¥8,155.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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Data Sheet

SDS

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生物活性

Discription

SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). Induces CDK1-dependent apoptosis in human acute myeloid leukemia cell lines. Active in vivo.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A22510
分子式	C21H22N4O4
分子量	394.431
CAS号	1259484-97-3
SMILES	O=C(C1=CC(C2=CC=C(OC)C=C2)=NN1)N/N=C(C3=CC=C(OC)C(OC)=C3)\C
其他名称	SKI-178, SKI 178, SKI178.
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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