SLV-2436
目录号: A20294
MNK1 and MNK2 inhibitor
SLV-2436 是一种高效的 ATP-竞争性抑制剂,针对 MNK1 和 MNK2 具有很强的抑制作用,其半抑制浓度(IC50)分别为 10.8 nM 和 5.4 nM。
Discription | SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8 ?nM and 5.4 nM, respectively. | ||
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Targets |
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目录号 | A20294 |
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分子式 | C19H15ClN4O |
分子量 | 350.8 |
CAS号 | 2095704-43-9 |
SMILES | O=C1C=CC(C2=CC3=C(C=C2)C(N)=NN3)=CN1CC4=CC=CC(Cl)=C4 |
其他名称 | SLV2436, SLV 2436, SEL201-88, SEL-201-88, SEL 201-88; SEL-201, SEL201, SEL 201 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 66 mg/mL (188.14 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (14.25 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.51 mL | 142.53 mL | 285.06 mL |
0.5 mM | 5.7 mL | 28.51 mL | 57.01 mL |
1 mM | 2.85 mL | 14.25 mL | 28.51 mL |
5 mM | 0.57 mL | 2.85 mL | 5.7 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2