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(Z)-SMI-4a

目录号: A11945
Pim 抑制剂
SIM-4a 是一种 Pim 激酶抑制剂,通过激活 AMPK 来阻断 mTORC1 活性。主要针对 Pim-2,对其他丝氨酸/苏氨酸激酶或酪氨酸激酶的抑制作用不显著。
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规格 价格 库存 数量
5mg
¥280.00
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10mg
¥420.00
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25mg
¥840.00
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50mg
¥1,540.00
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100mg
¥2,310.00
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10mM * 1mL in DMSO
¥315.00
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用(Z)-SMI-4a发表的1篇文献
  • Liong S, .et al. , Placenta, 2017, May;53:101-112 PMID: 28487013
  • 生物活性
    Discription SIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK. Mostly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.
    产品信息
    目录号 A11945
    分子式 C11H6F3NO2S
    分子量 273.2
    CAS号 327033-36-3
    SMILES O=C(NC/1=O)SC1=C/C2=CC=CC(C(F)(F)F)=C2
    其他名称 SMI4a
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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