SNIPER(ABL)-058
目录号: A19616
SNIPER(ABL)-058,通过连接体将伊马替尼(ABL抑制剂)与LCL161衍生物(IAP配体)结合,通过连接体实现,能够以DC50为10微摩尔的浓度降低BCR-ABL蛋白的表达。
Discription | SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM. |
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目录号 | A19616 |
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分子式 | C62H75N11O9S |
分子量 | 1150.39 |
CAS号 | 2222354-61-0 |
SMILES | CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCOC4=CC(C(C5=CSC([C@H]6N(C([C@H](C7CCCCC7)NC([C@H](C)NC)=O)=O)CCC6)=N5)=O)=CC=C4)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2