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SNS-314 mesylate

目录号: A10851
Aurora 抑制剂
SNS-314 Mesylate 是一种强效且选择性的 Aurora A、Aurora B 和 Aurora C 抑制剂,其半抑制浓度(IC50)分别为 9 nM、31 nM 和 3 nM。相比之下,它对 Trk A/B、Flt4、Fms、Axl、c-Raf 和 DDR2 的抑制作用较弱。目前处于临床试验第一阶段。
Grouped product items
规格 价格 库存 数量
2mg
¥175.00
现货
5mg
¥350.00
现货
10mg
¥560.00
现货
25mg
¥1,190.00
现货
50mg
¥1,785.00
现货
100mg
¥2,835.00
现货
10mM * 1mL in DMSO
¥420.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A10851
分子式 C18H15ClN6OS2.CH4O3S
分子量 527
CAS号 1146618-41-8
SMILES CS(=O)(=O)O.C1=CC(=CC(=C1)Cl)NC(=O)NC2=NC=C(S2)CCNC3=NC=NC4=C3SC=C4
其他名称 SNS314
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO Warmed: 80 mg/mL (151.79 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL (1.89 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.98 mL 94.88 mL 189.75 mL
0.5 mM 3.8 mL 18.98 mL 37.95 mL
1 mM 1.9 mL 9.49 mL 18.98 mL
5 mM 0.38 mL 1.9 mL 3.8 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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