SNX-5422 Mesylate

Name: SNX-5422 Mesylate
SKU: A21512

目录号: A21512

Hsp90 inhibitor

SNX-5422 Mesylate Chemical Structure

CAS NO. 1173111-67-5

SNX-5422 Mesylate (PF-04929113 Mesylate), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37?nM.

库存：现货

规格	价格	数量
5 mg	￥ 1,134.00
10 mg	￥ 1,953.00
50 mg	￥ 5,796.00
100 mg	￥ 11,592.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

SNX-5422 Mesylate (PF-04929113 Mesylate), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37?nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.19 mL	80.95 mL	161.91 mL
0.5 mM	3.24 mL	16.19 mL	32.38 mL
1 mM	1.62 mL	8.1 mL	16.19 mL
5 mM	0.32 mL	1.62 mL	3.24 mL

*The above data is based on the productmolecular weight 617.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21512
作用机制	Inhibitor (抑制剂)
M. Wt	617.64
Formula	C26H34F3N5O7S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1173111-67-5
Synonyms	PF-04929113 (Mesylate), PF04929113,PF-04929113
SMILES	CS(=O)(O)=O.O=C1CC(C)(C)CC2=C1C(C(F)(F)F)=NN2C3=CC=C(C(N[C@@H]4CC[C@@H](OC(CN)=O)CC4)=C3)C(N)=O