目录号
产品名
应用
产品描述
文献引用
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Na+ channel blocker
Amiloride hydrochloride 是一种 Na+ 通道阻断剂,同时也抑制 TRPP3 通道 和 Na+/H+ 交换器 (NHE)。- Yu Y, .et al. , Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
- Thomas D. Williams, .et al. , J Cell Sci, 2018, Mar 15; 131(6): jcs213736 PMID: 29440238
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Na+/H+-exchange inhibitor
FR183998 自由碱是一种强效的Na+/H+交换抑制剂,通过测量大鼠淋巴细胞、大鼠和人类血小板的内部氢离子浓度(pHi)变化,其IC50分别为0.3 nM、3.1 nM和6.5 nM。 -
NHE3 inhibitor
Tenapanor 作为钠-质子交换体 NHE3 的抑制剂发挥作用。这种反向转运蛋白存在于肾脏和肠道中,通常用于调节体内吸收和分泌的钠的水平。- Mahdi Amiri, .et al. , Am J Physiol Cell Physiol, 2024, Mar 1;326(3):C829-C842 PMID: 38223928
- Kuniko Hunter, .et al. , Tissue Eng Part A, 2022, Nov 18 PMID: 36274231
- Xingjie Tan, .et al. , Authorea, 2022, May 25
- Kunyan Zhou, .et al. , Am J Physiol Cell Physiol, 2021, Sep 1;321(3):C471-C488 PMID: 34288721
- Qinghai Tan, .et al. , Br J Pharmacol, 2021, Mar;178(5):1018-1036 PMID: 33179259
- Y Liu, .et al. , Biochem Pharmacol, 2020, May 16;178:114040 PMID: 32422138
- Yu Y, .et al. , Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
- Thammayon N, .et al. , Amino Acids, 2017, Apr;49(4):725-734 PMID: 27981415
- Charoenphandhu N, .et al. , Mol Cell Biochem, 2017, Mar;427(1-2):201-208 PMID: 27995414
- Jantarajit W, .et al. , Am J Physiol Cell Physiol, 2017, Jul 1;313(1):C118-C129 PMID: 28490422
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Na+/H+ exchange inhibitor
Eniporide hydrochloride (EMD-96785 hydrochloride) 是一种强效的 Na+/H+ 交换抑制剂。