Sorafenib (D3)

Name: Sorafenib (D3)
SKU: A21489
Price: 525 CNY
Rating: 5 (288 reviews)

目录号: A21489

Raf/VEGFR3 inhibitor

Sorafenib D3（Bay 43-9006 D3）是标记了氘的Sorafenib。Sorafenib是一种多激酶抑制剂，其IC50分别为6 nM、20 nM和22 nM，针对Raf-1、B-Raf和VEGFR-3。

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Grouped product items
规格	价格	库存
1mg	¥525.00	现货
5mg	¥1,330.00	现货
10mg	¥2,450.00	现货
25mg	¥4,095.00	现货
50mg	¥5,950.00	现货
100mg	¥8,015.00	现货
*10mM 1mL in DMSO**	¥1,435.00	现货
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Data Sheet

SDS

Other Forms of Sorafenib (D3)

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生物活性

Discription	Sorafenib D3 (Bay 43-9006 D3) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.

产品信息

目录号	A21489
分子式	C21H13D3ClF3N4O3
分子量	467.84
CAS号	1130115-44-4
SMILES	O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=C1)NC([2H])([2H])[2H]
其他名称	Bay 43-9006 (D3)
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (196.65 mM)
	Water	Insoluble
	Ethanol	6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.37 mL	106.87 mL	213.75 mL
0.5 mM	4.27 mL	21.37 mL	42.75 mL
1 mM	2.14 mL	10.69 mL	21.37 mL
5 mM	0.43 mL	2.14 mL	4.27 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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