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Sorafenib

目录号: A17857

Raf/VEGFR3 抑制剂

Sorafenib(Bay 43-9006)是一种强效的口服多激酶抑制剂,其半抑制浓度(IC50)分别为6 nM、20 nM和22 nM,针对Raf-1B-RafVEGFR-3
Grouped product items
规格 价格 库存 数量
50mg
¥175.00
现货
100mg
¥280.00
现货
500mg
¥385.00
现货
1g
¥595.00
现货
10mM * 1mL in DMSO
¥175.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription Sorafenib (Bay 43-9006) is a potent, orally active multikinase inhibitor with IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A17857
分子式 C21H16ClF3N4O3
分子量 464.83
CAS号 284461-73-0
SMILES O=C(NC(C=C1)=CC=C1OC2=CC(C(NC)=O)=NC=C2)NC3=CC=C(Cl)C(C(F)(F)F)=C3
其他名称 Bay 43-9006, Bay-43-9006, Bay43-9006
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO Warmed: 59 mg/mL (126.92 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5%DMSO+45%PEG400+50%H2O 0.35 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.51 mL 107.57 mL 215.13 mL
0.5 mM 4.3 mL 21.51 mL 43.03 mL
1 mM 2.15 mL 10.76 mL 21.51 mL
5 mM 0.43 mL 2.15 mL 4.3 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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