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SP600125

目录号: A10860
JNK 抑制剂
SP600125 是一种 JNK 抑制剂,对 JNK-1 和 JNK-2 的 IC50 为 40 nM,对 JNK-3 的 IC50 为 90 nM。
Grouped product items
规格 价格 库存 数量
5mg
¥175.00
现货
10mg
¥245.00
现货
50mg
¥280.00
现货
100mg
¥455.00
现货
200mg
¥595.00
现货
500mg
¥1,015.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用SP600125发表的8篇文献
  • Peiling Zhang, .et al. , Regen Biomater, 2023, Sep 7:10:rbad079 PMID: 38020237
  • Tetsuya Kouno, .et al. , J Biol Chem, 2022, Jul;298(7):102056 PMID: 35605662
  • Mark P Roberto, .et al. , Immunity, 2021, Aug 10;54(8):1807-1824.e14 PMID: 34380064
  • Yang PM, .et al. , Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
  • Byungki Jang, .et al. , Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055
  • Yuki Haga, .et al. , PLoS One, 2017, 12(3): e0174153 PMID: 28323861
  • Jia-Shiuan Tsai, .et al. , PLoS One, 2016, 11(1): e0147011 PMID: 26751215
  • Choe YJ, .et al. , Int J Oncol., 2014, 44(3):761-8. PMID: 24366007
  • 生物活性
    Discription SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A10860
    分子式 C14H8N2O
    分子量 220.2
    CAS号 129-56-6
    SMILES C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 43 mg/mL (195.25 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 45.41 mL 227.07 mL 454.13 mL
    0.5 mM 9.08 mL 45.41 mL 90.83 mL
    1 mM 4.54 mL 22.71 mL 45.41 mL
    5 mM 0.91 mL 4.54 mL 9.08 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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