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Spastazoline

Spastazoline

Name: Spastazoline
SKU: A19432

目录号: A19432

spastin inhibitor

Spastazoline Chemical Structure

CAS NO. 2351882-11-4

Spastazoline is a potent and selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC50 of 99 nM for Human spastin. Spastazoline shows no effect on ATPase activity of a recombinant human VPS4.

库存：现货

规格	价格	数量
5 mg	￥ 1,008.00
10 mg	￥ 1,736.00
50 mg	￥ 5,152.00
100 mg	￥ 10,304.00

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生物活性

溶解度 *

In vitro	DMSO	69 mg/mL (180.38 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (47.05 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.14 mL	130.72 mL	261.43 mL
0.5 mM	5.23 mL	26.14 mL	52.29 mL
1 mM	2.61 mL	13.07 mL	26.14 mL
5 mM	0.52 mL	2.61 mL	5.23 mL

*The above data is based on the productmolecular weight 382.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19432
M. Wt	382.51
Formula	C20H30N8
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2351882-11-4
SMILES	CC(C)(C)C1=CC(NC2=NC(N3CCN[C@H](C(C)C)C3)=NC4=C2C=CN4)=NN1