Spautin-1
Spautin-1 是一种新型的自噬抑制剂，IM 抑制 K562 细胞生长的 IC50 为 1.03μM。相比之下，与 Spautin-1 的联合处理增强了 IM 对细胞活性的抑制，IC50 为 0.45μM。
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Adooq用户使用Spautin-1发表的2篇文献
生物活性
| Discription | Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A12942 |
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| 分子式 | C15H11F2N3 |
| 分子量 | 271.26 |
| CAS号 | 1262888-28-7 |
| SMILES | FC1=CC(C(NCC2=CC=C(F)C=C2)=NC=N3)=C3C=C1 |
| 其他名称 | Spautin 1, Spautin1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 51 mg/mL (188.01 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (25.8 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.87 mL | 184.33 mL | 368.65 mL |
| 0.5 mM | 7.37 mL | 36.87 mL | 73.73 mL |
| 1 mM | 3.69 mL | 18.43 mL | 36.87 mL |
| 5 mM | 0.74 mL | 3.69 mL | 7.37 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1262888-28-7 | 1262888-28-7 供应商 | 1262888-28-7 花费 | 1262888-28-7 生产商 | 订购 1262888-28-7 | 1262888-28-7 代理商