SPDP

Name: SPDP
SKU: A20578
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A20578

short-chain crosslinker

SPDP（SPDP 交联剂）是一种短链交联剂，用于通过 NHS 酯和吡啶二硫醇反应基团实现胺基与巯基的偶联，形成与半胱氨酸巯基可裂解（可还原）的二硫键。它是一种可被谷胱甘肽裂解的 ADC 连接器，用于抗体药物偶联物（ADCs）。

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Grouped product items
规格	价格	库存
10mg	¥315.00	现货
25mg	¥665.00	现货
50mg	¥1,120.00	现货
100mg	¥1,995.00	现货
200mg	¥3,640.00	现货
500mg	¥7,035.00	现货
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Data Sheet

SDS

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生物活性

Discription

SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).

Targets

Target	Value

产品信息

目录号	A20578
分子式	C12H12N2O4S2
分子量	312.36
CAS号	68181-17-9
SMILES	O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2
其他名称	SPDP Crosslinker
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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